Skip to content
A frosted jar of Dr.Primal TUDCA 500mg on a stone kitchen worktop in morning light
TUDCA 500mg · two capsules daily

Keep eating what you love.

For people whose gallbladder is gone, or whose bile is not arriving when the food does. One ingredient, 500mg of TUDCA a day, studied for supporting bile flow and normal fat digestion.

£25.00/mo · £0.84 per day 4.8 out of 5 stars · 1051 reviews
Recognition

Are you any of these?

  • The surgery was meant to be the end of it. Now I plan my whole day around a toilet.
  • Sludge and a low ejection fraction. I want to keep the organ if I honestly can.
  • Ox bile worked for three weeks, then stopped. So what do people take next?
  • Twenty grams of fat a day, six safe meals. My hair is falling out.
  • Years of being told it was anxiety. I stopped going and started reading instead.
  • Three weeks in, no change, and I assume I am doing it wrong. Morning or night?
That is me
Mechanism

Bile is the part nobody explains.

Bile keeps moving

TUDCA is a bile acid. Taken with food, it supports the flow that carries fats and waste out of the liver and into the gut.

Cells under less strain

It has been studied as a chemical chaperone, easing the stress that builds inside liver cells when they are working hard.

Fat gets easier

Bile flow supports normal fat digestion, which is the part most people notice first.

Bile keeps moving Supports normal fat digestion Studied as a chemical chaperone One ingredient, 500mg Vegetable capsule, nothing else Two capsules daily
Formulation

One ingredient. Nothing hiding behind it.

No blends, no proprietary complexes, no fillers to make the capsule feel full.

TUDCA per serving
500mg
Other active ingredients
None
Capsule
Vegetable cellulose
Dose
Two capsules daily
Empty vegetable capsule shells on a warm stone surface
Reviews

Past experience from our customers.

Verified purchases, edited only for length.

5 out of 5 stars
Gallbladder out in 2019 and fatty meals had been a gamble since. Three weeks in, that gamble is mostly gone.
Marcus D.
4 out of 5 stars
Taking it because my GGT crept up. I cannot tell you what my bloods look like yet, but digestion is calmer and I am sticking with it.
Priya S.
5 out of 5 stars
Carnivore for two years and fat was still sitting heavy. Taking it with the first meal sorted that out.
Tom H.
5 out of 5 stars
On TRT and wanted something for the liver that was not a twelve-herb blend. One ingredient, one dose, nothing else in the capsule. Easy decision.
Dan R.
4 out of 5 stars
Bloating after any oily meal, plus a sluggish gut. Two weeks before I noticed anything, then a clear difference.
Hannah W.
5 out of 5 stars
Enzymes flagged at a medical, so I went looking for bile acids rather than another blend. Straightforward label, no theatre.
Ade O.
5 out of 5 stars
Gallbladder out in 2014. The first month I did not notice much. The second month I stopped planning my days around the bathroom.
Karen M.
4 out of 5 stars
I train fasted and eat one big meal at night. The food coma after it used to write off my evening. Milder now, most nights.
Tom S.
5 out of 5 stars
Bought it for my husband after his scan came back clear but fried food still would not agree with him. He eats with the rest of us again.
Priya D.
4 out of 5 stars
Two capsules with dinner, that is the whole routine. No taste, no repeating on me, and the Sunday roast sits like it used to.
Geoff L.
5 out of 5 stars
Sceptical, because I have a drawer full of things that did nothing. This one is on its third reorder, which says more than I can.
Sandra P.
4 out of 5 stars
My ALT was the reason I started. I retest in the spring, but meals sit lighter and that alone keeps me taking it.
Colin B.
4.8 out of 5 stars · 1051 reviews
Why we exist

We kept it simple. One ingredient, one dose.

We are not here to sell you a cocktail of inadequate doses. One ingredient, at the amount that has actually been studied, so you can tell whether it is working.

Shop TUDCA 500mg
500mg TUDCA per serving One ingredient, plus a vegetable shell Two capsules daily No fillers or bulking agents

One email a month, no theatre.

What we have read, what we are testing, and when the next product is ready. No offers you did not ask for.

4.8 out of 5 stars · 1051 reviews
Before you buy

The three questions we are asked most.

I take prescription medication. Is TUDCA a problem?

Bile acids can affect how some medicines are absorbed, and TUDCA is not suitable alongside certain treatments. Speak to your GP or pharmacist before you start, particularly if you take medication for cholesterol, thyroid, immunosuppression, or blood thinning. We would rather you checked than guessed.

Is it safe on keto or carnivore?

Yes, and it is one of the most common reasons people take it. A very high-fat diet asks a lot of your bile acid pool, and TUDCA has been studied for supporting bile flow. Take two capsules with your first fat-containing meal of the day.

How soon after gallbladder surgery can I start?

Wait until your surgical team has signed off your recovery and cleared you to reintroduce fat, then start with two capsules with food. Most people notice the difference over two to three weeks rather than in the first few days. This is a slow build, and we would rather say so.

Welcome offer