- 100% Purity TUDCA
- 30-Day Guarantee
- 1,000+ sold this week
TUDCA 500mg
A water-soluble bile acid for people whose bile does not move the way it used to — after gallbladder removal, on a high-fat diet, or when a blood test came back higher than you would like.
- Healthier Bile Flow
- Helps you digest fat
- Gallbladder comfort
- Protects liver cells
- Eases fatty-meal discomfort
- Mitochondrial function
- 100% Purity
TUDCA - 30-Day
Guarantee - 1,000+ sold
this week
- Free UK delivery on every subscription
- One ingredient, 500mg per serving
- Vegan capsule, no fillers
- 30-day money-back guarantee
What one serving is doing
TUDCA is a food supplement, so the language here is deliberately careful. These are supportive roles, not cures.
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Supports healthy bile flow
Bile carries fats, cholesterol and waste out of the liver. TUDCA is itself a bile acid, and a water-soluble one — which is why it still works when there is no gallbladder to concentrate it.
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Protects liver cells under load
It acts as a chemical chaperone, helping proteins fold correctly and easing endoplasmic reticulum stress inside the hepatocyte.
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Helps you digest fat
Better bile flow means better emulsification. This is the change people notice first, usually within two to three weeks.
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Supports mitochondrial function
TUDCA has been studied for its effect on mitochondrial membrane stability and cellular energy production.
Three places TUDCA shows up
TUDCA is absorbed, joins your own bile pool, and travels the same route your body already uses.
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Bile ducts
Keeps the flow moving
A more water-soluble bile pool means less back-pressure in the ducts and easier passage into the small intestine.
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Liver cell
Eases the load inside
As a chemical chaperone it supports correct protein folding and reduces endoplasmic reticulum stress in the hepatocyte.
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Small intestine
Helps you break down fat
Bile emulsifies dietary fat. Better emulsification is why fatty meals stop feeling like an event.
What customers report back
Self-reported, from a survey of Dr.Primal customers at twelve weeks. Figures to be confirmed before launch.
- 82% said fatty meals were easier after 12 weeks
- 4.8/5 average rating from 412 verified customers
- 3 weeks median time to a first noticed change
- 9 in 10 reordered after their first bottle
Six reasons people start
Most people arrive at TUDCA sideways — through a blood test, a surgery, or a diet that leans hard on fat. Pick the one that sounds like you.
Swipe through and pick the one that sounds like you.
After gallbladder removal
No reservoir means bile trickles rather than surges. Fat-heavy meals are the tell.
Keto and carnivore
A high-fat diet puts a standing demand on bile production that most people never think about.
On TRT or oral compounds
Anything that raises the liver's workload raises the case for bile-side support.
Raised liver enzymes
ALT, AST or GGT drifting up on a routine panel is the most common trigger for a first order.
Bile-driven constipation
Bile acids are a natural motility signal in the colon. Low flow can slow everything down.
SIBO and bloating
Bile is antimicrobial in the small intestine. When flow drops, overgrowth has an easier time.
Swipe for all six
Two lines on the label
| Ingredient | Per serving |
|---|---|
| TUDCATauroursodeoxycholic acid | 500 mg |
| Capsule shellHypromellose | — |
Nutrient Reference Value not established. No magnesium stearate, no rice flour, no colourings, no anti-caking agents.
How to take: two capsules daily in the morning, with or just before food. If you have no gallbladder, take them with your largest meal instead.
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TUDCA
Tauroursodeoxycholic acid — the taurine-conjugated form of UDCA. Water-soluble, which is why it works without a gallbladder.
500mg per serving Single ingredient Two a day -
Hypromellose capsule
A plant-based capsule shell. That is the entire rest of the formula — there is nothing else in the bottle.
Vegan No fillers
Your timeline, week by week
Nothing here happens overnight. Here is a realistic timeline, based on what TUDCA has been studied for and what our customers report.
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Days 1–7
Nothing much, and that is normal
- A few people notice looser stools as bile flow shifts
- If your stomach objects, move the capsules to a meal
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Weeks 2–3
Meals sit differently
- Fat-heavy food stops feeling like a decision
- Less bloating in the evening
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Weeks 4–8
Digestion steadies
- More consistent bowel habits
- Many report steadier energy after meals
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Weeks 8–12
Worth retesting
- If you started because of a blood panel, retest now
- Keep going — the benefit is in the consistency
4.8 out of 5, from 412 verified customers
Verified purchases. Edited only for length.
Gallbladder out in 2019 and fatty meals had been a gamble since. Three weeks in, that gamble is mostly gone.
Taking it because my GGT crept up. I cannot tell you what my bloods look like yet, but digestion is calmer and I am sticking with it.
Carnivore for two years and fat was still sitting heavy. Taking it with the first meal sorted that out.
On TRT and wanted something for the liver that was not a twelve-herb blend. One ingredient, one dose, nothing else in the capsule. Easy decision.
Bloating after any oily meal, plus a sluggish gut. Two weeks before I noticed anything, then a clear difference.
Enzymes flagged at a medical, so I went looking for bile acids rather than another blend. Straightforward label, no theatre.
Gallbladder out in 2014. The first month I did not notice much. The second month I stopped planning my days around the bathroom.
I train fasted and eat one big meal at night. The food coma after it used to write off my evening. Milder now, most nights.
Bought it for my husband after his scan came back clear but fried food still would not agree with him. He eats with the rest of us again.
Two capsules with dinner, that is the whole routine. No taste, no repeating on me, and the Sunday roast sits like it used to.
Sceptical, because I have a drawer full of things that did nothing. This one is on its third reorder, which says more than I can.
My ALT was the reason I started. I retest in the spring, but meals sit lighter and that alone keeps me taking it.
Can I take TUDCA if my gallbladder has been removed?
Yes — it is one of the most common reasons people take it. Without a gallbladder, bile drips into the gut continuously rather than being released in a concentrated burst. TUDCA is a water-soluble bile acid, so it supports that flow. Take it with your largest meal of the day.
How long before I notice anything?
Digestive changes are usually the first thing people report, typically within two to three weeks. Anything you would measure on a blood panel takes longer — retest after 8 to 12 weeks of consistent use.
How does the subscription work, and how do I cancel?
Your first order ships the next working day, then again every one, three or five months depending on the size you chose. Cancel, pause or change the date from your account or by replying to any of our emails — there is no phone menu and no minimum term.
Can I take it alongside my medication?
TUDCA is a food supplement and is not commonly known to interact with medication, but we are not able to give medical advice. If you take prescription medicine or have a diagnosed liver condition, speak to your GP or pharmacist before starting.
Why 500mg, and why two capsules?
Most human research on bile flow and liver markers sits in the 500–1,500mg per day range. A 500mg serving is two capsules, so you can start at the low end and build up on your own terms rather than opening capsules to split a scoop.
What is actually in the capsules?
500mg of tauroursodeoxycholic acid per serving, and hypromellose vegetable capsule shells. No magnesium stearate, no rice flour, no colourings.
Dr.Primal TUDCA 500mg is a food supplement and is not intended to diagnose, treat, cure or prevent any disease. Do not exceed the recommended dose. Not suitable if you are pregnant or breastfeeding. If you take prescription medication or have a diagnosed liver or gallbladder condition, speak to your GP or pharmacist first.
