Fatty Liver Symptoms: The Early Signs and What They Mean
Table of contents
- What to know
- What Are the Symptoms of Fatty Liver?
- What Are the Early Signs of Fatty Liver Disease?
- What Are the Symptoms of Advanced Fatty Liver?
- Fatty Liver Symptoms in Females: What Is Different?
- Are There Fatty Liver Symptoms on the Face or Skin?
- What About Alcohol-Related Fatty Liver?
- Is Fatty Liver More Common After Gallbladder Removal?
- How Is Fatty Liver Diagnosed?
- Who Should Get Checked for Fatty Liver?
- What Helps Fatty Liver?
- In Summary: Fatty Liver Symptoms
- Frequently Asked Questions
- References
Fatty liver usually causes no symptoms at all, and when it does, they tend to be vague: tiredness and a dull discomfort under the right ribs. Clearer signs, such as yellowing skin, swelling and easy bruising, belong to advanced scarring, so fatty liver is usually found by blood tests and scans, not by how you feel.
What to know
- Most people with fatty liver have no symptoms, and many find out from a routine blood test or scan.
- Early symptoms, when present, are tiredness and discomfort in the upper right side of the abdomen.
- Jaundice, swelling of the legs or belly, easy bruising and confusion point to advanced disease and need prompt care.
- Medical sources describe the same symptoms in women and men, while menopause, PCOS and diabetes in pregnancy change a woman's risk.
- Gradual weight loss of 3 to 5 percent can reduce liver fat, and larger losses can improve inflammation and scarring.
Fatty liver is one of the most common causes of liver disease in the US, affecting about 1 in 4 adults [1], and many of the people who have it do not know [2]. It usually turns up by accident, on a test done for something else, and the first reaction is to wonder what symptoms were missed.
Usually there were none to miss. This guide covers what fatty liver does and does not feel like, which signs mean real trouble, how it is found and what improves it.
What Are the Symptoms of Fatty Liver?
Fatty liver often has no symptoms, and when symptoms do appear, they are usually tiredness and discomfort in the upper right side of your abdomen [3]. Liver specialists note that most patients have no symptoms or only vague ones [2].
In 2023, international liver societies renamed nonalcoholic fatty liver disease (NAFLD) as metabolic dysfunction-associated steatotic liver disease, or MASLD, and its inflamed form, once called NASH, as metabolic dysfunction-associated steatohepatitis, or MASH [4, 1]. MASLD now means fat in the liver plus at least one cardiometabolic risk factor, such as a large waist, raised blood sugar, high blood pressure or abnormal blood fats, and no other cause such as heavy drinking [4].
Only about 1.5 to 6.5 percent of US adults have the inflamed form [1]. Even people whose disease has reached cirrhosis may have no symptoms [3].
What Are the Early Signs of Fatty Liver Disease?
None of the early signs is specific to the liver.
1. Tiredness
Feeling tired is one of the two symptoms most often described for fatty liver [3], but tiredness has many causes, from poor sleep to an underactive thyroid [5]. On its own it is a reason to review your risk factors.
2. Discomfort under the right ribs
Some people notice discomfort in the upper right side of the abdomen, where the liver sits [3]. Pain that builds to a steady, severe level and lasts 30 minutes or more is more typical of gallstones or the bile ducts [6], which deserve their own check.
3. A result on a blood test or scan
For many people the first sign is a slightly raised liver enzyme on a routine panel, or fatty liver noted on an ultrasound done for another reason [2]. Our guide to elevated liver enzymes explains those numbers.
What Are the Symptoms of Advanced Fatty Liver?
Clearer symptoms tend to appear once long-standing inflammation has caused significant scarring, called fibrosis, and eventually cirrhosis, although some people with cirrhosis still have none [3, 7]. Early in cirrhosis, people may feel weak, lose appetite or weight without trying, feel nauseated or itchy [7], or notice small, red, spider-like blood vessels on the skin [8].
As liver function worsens, get medical care promptly if you notice [7, 8]:
- yellowing of the skin or the whites of the eyes (jaundice)
- dark urine, or pale or clay-colored stools
- swelling in the lower legs, ankles or feet, or a swollen abdomen from fluid buildup
- bruising or bleeding easily
- confusion, trouble thinking, memory problems or changes in sleep
- signs of bleeding in the digestive tract, such as vomiting blood or black, tarry stools [9]
Vomiting blood, black, tarry stools or sudden confusion need emergency care: call 911 [9, 10].
Jaundice with dark urine and pale stools can also mean a blocked bile duct [11].
Fatty Liver Symptoms in Females: What Is Different?
Medical sources describe the same symptoms in women and men: usually none, sometimes tiredness and right-sided discomfort, and the same late signs [3, 7]. What differs for women is when the risk rises.
1. Menopause
Fatty liver is more common in women after menopause than before it [2]. A review of 12 studies found about 2.4 times the odds of fatty liver in postmenopausal women compared with premenopausal women, and the link held in the studies that adjusted for age and metabolic factors, though every study was a snapshot in time [12]. Our article on bloating in menopause covers this stage.
2. Polycystic ovary syndrome (PCOS)
Large studies have found fatty liver two to four times as often in women with PCOS, and insulin resistance appears to be the main driver [2].
3. Pregnancy
Diabetes during pregnancy is linked with fatty liver later in life: in a US study of 1,115 women followed for 25 years, 14 percent of those who had had gestational diabetes had fatty liver on a CT scan in midlife, compared with about 6 percent of those who had not, a link that seemed to run largely through type 2 diabetes developing later [13]. Acute fatty liver of pregnancy is a separate condition: it is rare, appears late in pregnancy and is a medical emergency [14].
Some online lists add heavy or missed periods to the symptoms in women, but the major medical sources do not list them as symptoms [3, 2], and they have their own causes worth raising with your doctor.
Are There Fatty Liver Symptoms on the Face or Skin?
Fatty liver itself has no recognized sign on the face. When doctors examine someone with possible fatty liver, they look for two different kinds of skin sign: those of insulin resistance and those of advanced liver disease [2].
The insulin-resistance sign is acanthosis nigricans, darker, thick, velvety skin in body folds such as the neck, armpits and groin, which is linked with insulin resistance, diabetes and obesity [15]. It is a sign of insulin resistance rather than of liver damage, and a reason to check blood sugar and the liver [15, 2]. Skin that darkens quickly or over wide areas is worth showing a doctor soon [15]. The signs of advanced disease are different: spider-like blood vessels on the skin, red palms, yellowing of the skin and eyes, easy bruising and itching [8, 2, 7]. Lists that link acne, puffiness or dark circles to a "fatty liver face" do not come from these medical sources.
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What About Alcohol-Related Fatty Liver?
Heavy drinking can cause fatty liver on its own, known as alcohol-associated liver disease [1]. Its symptoms follow the same pattern, often none early on and the same late signs once scarring is advanced [16, 10], and in the early stage, stopping drinking can reverse the damage [17].
Alcohol also adds to metabolic fatty liver. Heavy drinking speeds scarring, and even drinking at a level US liver guidance calls moderate, about two to three drinks a day for women and two to four for men, has been linked with more advanced scarring, particularly in people with obesity or type 2 diabetes [2, 18].
Is Fatty Liver More Common After Gallbladder Removal?
Studies find fatty liver somewhat more often after gallbladder removal, but they show an association, not proof that surgery causes it. A 2023 review of seven studies found about 54 percent higher odds, clear in US studies but not European ones, and rated the evidence low certainty [19]. In a large Korean study, the extra risk was concentrated in people with three or more cardiometabolic risk factors and was not significant in those with fewer [20].
Shared roots appear to explain much of the link. Gallstones and fatty liver share central obesity, insulin resistance and diabetes [21], and in a Dutch population study the link disappeared once metabolic factors were taken into account [22]. Fatty liver found after surgery does not by itself mean the operation damaged your liver. Our guide to whether not having a gallbladder affects your liver covers these studies in full, and our article on weight gain after gallbladder removal covers weight.
The digestive side of life after surgery is a separate question from the liver. For heaviness after richer meals, Dr.Primal's TUDCA, a hydrophilic, or water-loving, bile acid that occurs naturally in small amounts in human bile [23], is used to support healthy bile flow and fat digestion.
How Is Fatty Liver Diagnosed?
Fatty liver is diagnosed with blood tests and imaging, which look for scarring as well as fat, because scarring shapes the outlook [2].
1. Liver enzymes (ALT and AST)
ALT and AST are enzymes made mainly in the liver and measured on a standard liver panel [24]. They can be raised in fatty liver or entirely normal, so a normal panel does not rule it out, and liver specialists suggest treating an ALT above 30 U/L as abnormal as a general rule [2].
2. Ultrasound
A standard abdominal ultrasound can show fat in the liver, but it misses milder amounts, especially in people with obesity. CAP, measured during an elastography scan, gives only a rough estimate of liver fat, and an MRI method called PDFF measures it most accurately [2].
3. The FIB-4 score
FIB-4 is a simple calculation from your age, ALT, AST and platelet count that estimates the likelihood of advanced scarring [2]. A score below 1.3 (below 2.0 if you are over 65) means advanced fibrosis is unlikely and you can be rechecked periodically by your primary care doctor, though the score is less accurate under age 35 [2].
4. Elastography
Above that cutoff, the next step is usually a liver stiffness scan (vibration-controlled transient elastography, often known as FibroScan) or a blood test called ELF, with an MRI stiffness scan if results are unclear [2]. A stiffness reading below 8 kPa can rule out advanced fibrosis [2].
Who Should Get Checked for Fatty Liver?
Because fatty liver is usually silent, testing targets people with risk factors. Liver specialists recommend assessing people with type 2 diabetes, obesity with metabolic complications, a family history of cirrhosis or significant alcohol use [2]. Between 30 and 75 percent of people with type 2 diabetes have fatty liver, and close relatives of people with cirrhosis from fatty liver have a much higher risk of advanced scarring [2].
Overweight, insulin resistance, abnormal blood fats and metabolic syndrome raise the risk [3], and higher rates are reported in women with PCOS [2]. If any of these apply to you, ask your doctor whether a liver panel and a FIB-4 score make sense. Our questions to ask your doctor can help.
What Helps Fatty Liver?
Weight loss is the main treatment doctors recommend [25], and the benefit tends to grow with the amount lost [2]. For people who are overweight, losing at least 3 to 5 percent of body weight can reduce fat in the liver, and 7 to 10 percent may be needed to reduce inflammation and scarring [25]. US liver guidance puts the figure for MASH and scarring at generally more than 10 percent [2]. Slow loss is safer, because rapid weight loss and malnutrition can make liver disease worse [25].
1. Change the pattern of eating
Different eating patterns, such as low-carbohydrate, low-fat or Mediterranean, appear roughly equal at improving fatty liver, and a Mediterranean-style pattern is often recommended because it is sustainable and good for the heart [2]. Diets high in calories, saturated fat, refined carbohydrates and sugar-sweetened drinks are linked with fatty liver, and excess fructose in particular raises the risk [2]. Our guide to the fatty liver diet turns this into meals.
2. Move more
Regular moderate exercise adding up to about 150 minutes a week can prevent or improve fatty liver in some studies [2], in line with the 150 to 300 minutes a week advised for all adults [26].
3. Cut back on alcohol
Drinking less removes a factor that speeds liver scarring [2], and our guide to alcohol after gallbladder removal has more. Coffee has a favorable link: three or more cups a day, even decaf, is associated with less advanced liver disease in observational studies [2].
4. Treat the conditions that travel with it
Heart disease and cancers outside the liver are the most common causes of death in people with fatty liver, ahead of liver disease itself [2], so managing blood sugar, blood pressure and cholesterol is part of treating fatty liver [2]. For people with MASH and moderate to advanced scarring but no cirrhosis, your doctor may also prescribe an FDA-approved medicine such as resmetirom (Rezdiffra) or semaglutide injection (Wegovy), each used alongside diet and exercise [27, 28].
No dietary supplement is FDA-approved to treat fatty liver [29], and products sold as liver cleanses can be unsafe [30]. Our articles on liver detox and liver health supplements look at the evidence.
In Summary: Fatty Liver Symptoms
Fatty liver usually causes no symptoms, or only tiredness and discomfort under the right ribs. Jaundice, swelling, easy bruising and confusion belong to advanced scarring and need prompt care. Menopause, PCOS and diabetes in pregnancy raise a woman's risk, and the link with gallbladder removal appears to come mostly from shared metabolic roots.
Because symptoms are a poor guide, the useful step is a liver panel and FIB-4 score if you have risk factors, then gradual weight loss, more movement and less alcohol if fat is found. If you want a starting point, our short digestion quiz is a quick way to put your digestion symptoms and habits in order.
For the studies themselves, see our evidence reviews on TUDCA, bile acids and gallbladder removal. Five neutral reviews of the studies in people, with methods, grades and sources.
Frequently Asked Questions
What are the three signs of a fatty liver?
There is no fixed set of three, because most people with fatty liver have no symptoms [2]. When signs appear, the three most often mentioned are tiredness, discomfort in the upper right side of the abdomen [3] and a raised liver enzyme or fatty liver seen on an ultrasound [2]. Yellowing skin, swelling and easy bruising point to advanced disease [7].
Can a fatty liver repair itself?
Yes, liver fat can go down when its causes are addressed. Losing 3 to 5 percent of body weight can reduce liver fat, and 7 to 10 percent may reduce inflammation and scarring [25]. US liver guidance puts the figure for scarring at generally more than 10 percent [2], so it helps to know from a FIB-4 score or stiffness scan whether you have any [2].
Should I worry if I have a fatty liver?
It deserves attention but rarely alarm. About a quarter of US adults have fatty liver, and only a small share have the inflamed form that can lead to cirrhosis [1]. Scarring is the best guide to what lies ahead, so ask about a FIB-4 score, and heart disease is a more common cause of death than liver disease in people with fatty liver [2].
Do people with no gallbladder have fatty liver?
Many do, as do many people who still have one, since about 24 percent of US adults have fatty liver [1]. Studies find it somewhat more often after gallbladder removal [19], but people who need the operation often share its risk factors, such as excess weight and insulin resistance [21], and some studies find no link at all [22, 31].
References
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- National Institute of Diabetes and Digestive and Kidney Diseases. Symptoms & causes of NAFLD & NASH. Last reviewed April 2021. NIDDK
- Rinella ME, Lazarus JV, Ratziu V, et al. A multisociety Delphi consensus statement on new fatty liver disease nomenclature. Hepatology. 2023;78(6):1966-1986. PubMed
- National Institute of Diabetes and Digestive and Kidney Diseases. Hypothyroidism (underactive thyroid). Last reviewed March 2021. NIDDK
- Cotton PB, Elta GH, Carter CR, Pasricha PJ, Corazziari ES. Rome IV. Gallbladder and Sphincter of Oddi Disorders. Gastroenterology. 2016. Published online ahead of print. doi:10.1053/j.gastro.2016.02.033. PubMed
- National Institute of Diabetes and Digestive and Kidney Diseases. Symptoms & causes of cirrhosis. Last reviewed June 2023. NIDDK
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- Jaroenlapnopparat A, Charoenngam N, Ponvilawan B, Mariano M, Thongpiya J, Yingchoncharoen P. Menopause is associated with increased prevalence of nonalcoholic fatty liver disease: a systematic review and meta-analysis. Menopause. 2023;30(3):348-354. PubMed
- Ajmera VH, Gunderson EP, VanWagner LB, Lewis CE, Carr JJ, Terrault NA. Gestational Diabetes Mellitus Is Strongly Associated With Non-Alcoholic Fatty Liver Disease. Am J Gastroenterol. 2016;111(5):658-664. PubMed
- Hadi Y, Kupec J. Acute Fatty Liver of Pregnancy. In: StatPearls. 2023. PubMed
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- Jophlin LL, Singal AK, Bataller R, et al. ACG Clinical Guideline: Alcohol-Associated Liver Disease. Am J Gastroenterol. 2024;119(1):30-54. PubMed
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This article is for general education and is not a substitute for advice from your doctor. TUDCA is sold as a dietary supplement. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.